Serveur d'exploration MERS

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Origin and evolution of pathogenic coronaviruses

Identifieur interne : 000868 ( Main/Exploration ); précédent : 000867; suivant : 000869

Origin and evolution of pathogenic coronaviruses

Auteurs : Jie Cui ; Fang Li [États-Unis] ; Zheng-Li Shi

Source :

RBID : PMC:7097006

Descripteurs français

English descriptors

Abstract

Severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) are two highly transmissible and pathogenic viruses that emerged in humans at the beginning of the 21st century. Both viruses likely originated in bats, and genetically diverse coronaviruses that are related to SARS-CoV and MERS-CoV were discovered in bats worldwide. In this Review, we summarize the current knowledge on the origin and evolution of these two pathogenic coronaviruses and discuss their receptor usage; we also highlight the diversity and potential of spillover of bat-borne coronaviruses, as evidenced by the recent spillover of swine acute diarrhoea syndrome coronavirus (SADS-CoV) to pigs.


Url:
DOI: 10.1038/s41579-018-0118-9
PubMed: 30531947
PubMed Central: 7097006


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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